أحمد مرزه حمزه جبار أبو دخن

Triaryl imidazole and quinoline derivatives are highly significant in pharmaceutical and medicinal chemistry due to their diverse biological activities. This paper explores an innovative green chemistry approach using CuFeO2 nanoparticles in ChCl-urea solvent as an efficient catalytic system for synthesizing these compounds. In this method, we demonstrate that CuFeO2 nanoparticles can effectively facilitate multicomponent reactions to prepare heterocyclic derivatives under ecofriendly conditions. Through this method, we synthesized a wide range of triaryl imidazoles and 2,4-substituted quinolines with high yields, showing that the catalyst’s efficiency is robust across various substrates. Notably, the CuFeO2 catalyst exhibited excellent reusability, maintaining its catalytic performance after being recycled up to nine times. These results highlight the effectiveness of this catalytic system in promoting green and sustainable chemistry.

Due to the fact that its structure and function comparable to those of reel human bone hydroxyapatite (HA) is regarded as an essential bio-ceramic component that generated a wide range of applications in the field of biomaterials. Consequently, the primary purpose of this study to produce a pure nanoparticles powder of hydroxyapatite through calcination process while the bovine bone is subjected to heat treatment at 800℃.

A series of symmetrical diaryliodonium salts were prepared successfully in high yields following the Olofsson procedure. These salts were stirred with aqueous solution of NaBF4 to exchange the OTf- anion to BF4-. Different conditions were investigated to fluorinate these salts, including fluorinating reagents, solvents, reaction time, and solvents. Only p-fluoroarenes without any isomers were obtained in high yields during the fluorination of these salts.

A simple and efficient halogenation pathway has been delivered with various diaryliodonium salts, containing an ortho alcoholic sidearm, and CuCl or CuBr to produce chloro arenes and bromo arenes in para position only without any ortho aromatic isomer. The reaction conditions include temperature(60 oC), solvent (DMF) and reaction time (2 hours)were optimized in order to obtain high yields of products.All products were isolated and characterized via 1H-NMR and 13C-NMR. With further investigation, these methods could be the main entrance to prepare herbicides, insecticides and bactericides containing haloarenes in their structures

The synthesis of benzothiazole and its derivatives has been the focus of many years by synthetic chemists due to its use in chemical and pharmaceutical fields. In this article, we have constructed copper (I) iodide supported on the magnetic Fe3O4 nanoparticles functionalized with Serine [Fe3O4-Serine-CuI] and evaluated its activity in the preparation of 2-substituted benzothiazoles via reactions of 2-iodoaniline and aromatic aldehydes with thiourea at refluxing water. The structure of Fe3O4-Serine-CuI nanocatalyst is well analyzed by several spectroscopic techniques. High reusability and well characterization of Fe3O4-Serine-CuI nanocatalyst, high purity and yields of products, aqueous conditions, and simple operation are several considerable advantages this catalytic system.

In recent years, the focus on taking out biologically active molecules from animals’ byproducts, especially from marine organisms have been increased. These sources play a major role in extracting collagen to be used as a biomaterial for medical applications and in the food industry. However, collagen-producing firms can be found all around the world, but not all of them kinds 100% pure collagen; instead, they make gelatin hydrolyzed collagen. These businesses lack additional collagen development. Therefore, extracting collagen from fish scales as a potential raw material and using it to study high-value applications might potentially produce an economic potential for anti-inflammatory protein.

Activated aromatics were reacted with two different fluoroidoane reagents 1 and 2 in the presence of triflic acid to prepare only the para-substituted diaryliodonium salts. With fluoroiodane 1 the unsymmetrical diaryliodonium salts contained an ortho-propan-2-ol sidearm, whereas the alcohol sidearm was eliminated to form an ortho-styrene sidearm in the reaction with fluoroiodane 2. Only the diaryliodonium salts containing a styrene sidearm were fluorinated successfully to deliver para-fluorinated aromatics in good yields.